By Ingalis A.G. (ed.)

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Cell Sci. 107, 2427–2437. 7. Gibson, C. , Watson, G. , and Myhra, S. (1996) Determination of the spring constants of probes for force microscopy/spectroscopy. Nanotechnology 7, 259–262. 8. Gibson, C. , Watson, G. , and Myhra, S. (1997) Scanning force microscopy calibrative procedures for ‘best practice’. Scanning 19, 564–581. 9. Putman, C. A. , van der Werf, K. , de Grooth, B. , van Hulst, N. , and Greve, J. (1994) Viscoelsticity of living cells allows high resolution imaging by tapping mode atomic force microscopy.

8. , Czajkowsky, D. , and Shao, Z. (1999) AFM tips: How sharp are they? J. Microsc. 196, 1–5. Artifacts in AFM 37 9. Taatjes, D. , Quinn, A. , Lewis, M. , and Bovill, E. G. (1999) Quality assessment of atomic force microscopy probes by scanning electron microscopy: Correlation of tip structure with rendered images. Microsc. Res. Tech. 44, 312–326. 10. Dinte, B. , Watson, G. , Dobson, J. , and Myhra, S. (1996) Artefacts in noncontact mode force microscopy: The role of adsorbed moisture. Ultramicroscopy 63, 115–124.

Nanomechanical Cantilever as Detectors The principle of detection is based on the functionalization of the complete cantilever surface with a layer that is sensitive to the compound to be investigated. , liquids or gas phase). The interaction of the analyte with the sensitive layer is transducted into a From: Methods in Molecular Biology, vol. 242: Atomic Force Microscopy: Biomedical Methods and Applications Edited by: P. C. Braga and D. , Totowa, NJ 39 40 Hegner and Arntz static deflection by inducing stress on one surface of the cantilever as the result of denser packing of the molecules (8) or a frequency shift in case of dynamic detection mode (9) as a result of changes in mass.

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Amateur telescope making by Ingalis A.G. (ed.)

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